Synthesis, Characterization, Invitro Thrombolytic Activity and Antimitotic Activity of Some Alkyl/Halo Substituted Cyanoacetyl Hydrazone Derivatives

Abstract

The majority of pharmaceutical products that mimic natural products with biological activity are heterocycles. Synthetic heterocyclic compounds can and do participate in chemical reactions in the human body. Moreover, all biological processes are expressed through chemical reaction. The present study describes about the synthesis and characterization and biological studies of novel alkyl/halo substituted cyanoacetyl hydrazone derivatives. The synthesized compounds characterized by FT-IR, ¹H-NMR and ¹³C-NMR spectral studies. The synthesized compounds subjected to antimitotic, invitro anti diabetic activities.

This in vitro study explores the antidiabetic properties of synthesized compounds and it can be considered as a potential for the management of type-II diabetes mellitus.  The synthesized compound subjected to preliminary antimitotic studies by Allium cepa root MERISTAMATIC CELLS.